Threonine
| Threonine | |
|---|---|
| Systematic name | (2S,3R)-2-Amino- 3-hydroxybutanoic acid |
| Abbreviations | Thr T |
| Chemical formula | C4H9NO3 |
| Molecular mass | 119.12 g mol-1 |
| Melting point | 256 °C |
| Density | ? g cm-3 |
| Isoelectric point | 5.60 |
| pKa | 2.20 8.96 |
| CAS number | [72-19-5] |
| EINECS number | 200-774-1 |
| SMILES | CC(O)C(N)C(=O)O |
| Image:Threonine.png | |
| Disclaimer and references | |
Threonine is one of the 20 natural amino acids. Nutritionally, in humans, threonine is an essential amino acid.
Threonine contains two chiral centers, so there are four possible stereoisomers of threonine, or two possible diastereomers of L-threonine. However, the name L-threonine is used for one single enantiomer, (2S,3R)-2-amino-3-hydroxybutanoic acid. The second diastereomer (2S,3S), which is rarely present in nature, is called L-allo-threonine.
The threonine side chain can undergo O-linked glycosylation.
Threonine can become phosphorylated through the action of a threonine kinase. In its phosphorylated form, it can be referred to as phosphothreonine.
Foods high in threonine are cottage cheese, poultry, fish, meat, lentils, and sesame seeds.
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| Alanine | Arginine | Asparagine | Aspartic acid | Cysteine | Glutamic acid | Glutamine | Glycine | Histidine | Isoleucine | Leucine | Lysine | Methionine | Phenylalanine | Proline | Serine | Threonine | Tryptophan | Tyrosine | Valine |
| Essential amino acid | Protein | Peptide | Genetic code |
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